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CASE REPORT
Year : 2019  |  Volume : 2  |  Issue : 2  |  Page : 104-106

Platelet-rich plasma protocols can potentiate vascular emboli: Contraindications to platelet-rich plasma


1 H. Ben Taub Department of Physical Medicine and Rehabilitation; Department of Orthopedic Surgery, Baylor College of Medicine, Houston, TX, USA
2 H. Ben Taub Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, TX, USA
3 H. Ben Taub Department of Physical Medicine and Rehabilitation, Baylor College of Medicine; Department of Physical Medicine and Rehabilitation, The University of Texas Health Science Center at Houston (UTHealth) McGovern Medical School, Houston; Human Performance Center, Bellaire, TX, USA

Correspondence Address:
Dr. Prathap Jayaram
Baylor College of Medicine, Houston, TX
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jisprm.jisprm_48_19

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Platelet-rich plasma (PRP) is a regenerative therapy strategy used to address surgical wounds, dermatological conditions, and musculoskeletal conditions, such as lateral epicondylosis. However, there exists significant uncertainty and speculation about antiplatelet agents' effects on PRP and optimal approaches to cessation of agents such as aspirin prior to PRP therapy. We present a rare case report that provides an example of temporary antiplatelet agent cessation complications in the context of a PRP therapy regimen for lateral epicondylosis, which was followed by microemboli to the brain. Given Class B evidence for PRP for lateral epicondylosis, we feel that this case of a nontraumatic brain injury sequelae can present more frequently given the increased popularity of this regenerative strategy, particularly if certain precautions are not evaluated.


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